By S. P. Borriello (auth.), S. Peter Borriello PhD. (eds.)
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Extra info for Antibiotic Associated Diarrhoea and Colitis: The role of Clostridium difficile in gastrointestinal disorders
Difficile. Raibaud and co-workers (1974) have shown that they can augment the outgrowth of clostridial spores from faecal specimens by the addition to the media of 1% sodium taurocholate and further that recovery of C. , 1980). We have routinely incorporated sodium taurocholate into our selective medium since 1979 (based on a presentation by Raibaud) and found this procedure improves 44 our recovery of ~. difficile. In addition we have noted that although the incorporation of sodium taurocholate into our medium resulted in higher yields of ~.
1978b); preparations, information regarding corticosteroids, exchange resins does not exist. to be mild, it may be most the efficacy of Lactobacillus antiperistaltic agents and anionic Because this type of diarrhea tends appropriate discontinue the offending antimicrobial. (and effective) simply to 36 SUMMARY Antimicrobial-associated diarrhea is often caused by Clostridium difficile; cytotoxin this disease can best be diagnosed by detection of fecal in a tissue culture assay and, when therapy is indicated, can be effectively treated with orally administered vancomycin.
Occasional case of antimicrobial-associated diarrhea attributable The to S. aureus should respond to treatment with oral vancomycin as outlined for C. difficile above. The infrequent cases of antimicrobial- associated diarrhea that appears to involve Campylobacter, Salmonella, Shigella, Yersinia, Entamoeba or Giardia should be treated the same as if antimicrobial therapy had not been a contributing factor; excellent reviews of these topics are available. Guidelines that does not for management of antimicrobial-associated diarrhea involve a recognized pathogen have not been developed.
Antibiotic Associated Diarrhoea and Colitis: The role of Clostridium difficile in gastrointestinal disorders by S. P. Borriello (auth.), S. Peter Borriello PhD. (eds.)