Marc L. Dubois's Action potential: Biophysical and cellular context, PDF

By Marc L. Dubois

ISBN-10: 161761579X

ISBN-13: 9781617615795

An motion strength (or nerve impulse) is a temporary alteration of the transmembrane voltage (or membrane strength) throughout an excitable membrane in an excitable mobilephone (such as a neuron or myocyte) generated by means of the job of voltage-gated ion channels embedded within the membrane. the simplest identified motion potentials are pulse-like waves of voltage that commute alongside the axons of neurons. This booklet reports examine on motion power together with an summary of the function of specialized axonal excitability ideas in realizing the results of irregular membrane excitability; the physiological implications of motion strength in characean cells; and, motion strength construction and the ion channel established procedure and others.

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Fast K+ currents act to dampen excitability following an action potential to prevent re-excitation and contribute to maintaining resting membrane potential (Chiu and Ritchie, 1984; Waxman and Ritchie, 1993). , 1995). , 2009). , 1998). , 2004; Roper and Schwarz, 1989). However the large size of the internode means that slow internodal K+ channels still make a significant contribution to resting membrane potential. , 2006). , 2006). , 1998). Slow K+ currents do not contribute to repolarization during the generation of a single impulse due to their slow kinetics.

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Action potential: Biophysical and cellular context, initiation, phases and propagation by Marc L. Dubois

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